Bored of academia? Sick of publish-or-perish and the grant-chasing treadmill? You've probably thought about building a career in the pharmaceutical industry, only to find a confusing world of unfamiliar terminology, requirements, and job descriptions. This book explains the many complexities of the pharmaceutical industry: the processes, the expectations, the skills you need to know and the careers you can enter - all laid out in an informative and jargon-free manner. For those who have started or want to start in the pharmaceutical industry, this book is a vital resource. What does it include? - An introduction to the entire drug development and manufacturing process. We examine how a drug goes from chemical entity to a final pharmaceutical; how drug batches are made, checked, and released to the market; we look at the marketing process, pharmacovigilance, and how processes change over time. - Industry expectations. We look at the knowledge you should learn during the first few weeks and months, attributes you should be cultivating, and how to work effectively with your manager. - Industry skills you need to succeed. We cover skills such as effective communication in all its forms, how to attend and run a meeting; how to organise information, how to cope with the sudden demands on your time and how to plan and execute projects succesfully. - Starting and building your pharmaceutical career. We describe the most common entry roles taken by life scientists entering industry and how you can develop your career beyond that initial step. - Finally our terminology list helps explain the multitude of pharmaceutical terms which you will come across in your career.
The productivity in pharmaceutical research and development faces intense pres sure. R&D expenditures of the major US and European companies have topped US$ 33 billion in 2003 compared to around US$ 13 billion just a decade ago. At the same time, the number of new drug approvals has dropped from 53 in 1996 to only 35 in 2003. Moreover, the protraction of clinical trials has significantly reduced the effective time of patent protection. The consequences are devastating. Monopoly profits have started to decline and the average costs per new drug have reached a re cord level of close to US$ 1 billion today. As a result, any failure of a new sub stance in the R&D process can lead to considerable losses, and the risks of introduc ing a new drug to the market have grown tremendously. Particularly if a company is highly dependent on just a handful of mega-selling blockbuster drugs, the risks can be even greater. For example, Pfizer generated about 90% of its worldwide revenues in 2002 with just 8 products. Any shortfall of a promising late-stage drug candidate would have left Pfizer with a gaping hole in its product portfolio. In order to deal with these risks, many pharmaceutical companies have started to organize their R&D in partnership. In fact, more than 600 alliances in pharmaceutical R&D are signed every year.
This book deals with various unique elements in the drugdevelopment process within chemical engineering science andpharmaceutical R&D. The book is intended to be used as aprofessional reference and potentially as a text book reference inpharmaceutical engineering and pharmaceutical sciences. Many of theexperimental methods related to pharmaceutical process developmentare learned on the job. This book is intended to provide many ofthose important concepts that R&D Engineers and manufacturingEngineers should know and be familiar if they are going to besuccessful in the Pharmaceutical Industry. These include basicanalytics for quantitation of reaction components– oftenskipped in ChE Reaction Engineering and kinetics books. In additionChemical Engineering in the Pharmaceutical Industryintroduces contemporary methods of data analysis for kineticmodeling and extends these concepts into Quality by Designstrategies for regulatory filings. For the current professionals,in-silico process modeling tools that streamlineexperimental screening approaches is also new and presented here.Continuous flow processing, although mainstream for ChE, is uniquein this context given the range of scales and the complex economicsassociated with transforming existing batch-plant capacity. The book will be split into four distinct yet related parts.These parts will address the fundamentals of analytical techniquesfor engineers, thermodynamic modeling, and finally provides anappendix with common engineering tools and examples of theirapplications.
Release on 2014-09-28 | by Ms Elisabeth Goodman,Mr John Riddell
Enhancing Research, Development and Manufacturing Performance
Author: Ms Elisabeth Goodman,Mr John Riddell
Pubpsher: Ashgate Publishing, Ltd.
Category: Business & Economics
Blending the authors’ considerable experiences with those of interviewees and with their retrospective and forward-looking perspectives, this volume explains how to apply Knowledge Management in a variety of environments in order to achieve improved efficiency, better decision making and enhanced innovation. This is achieved by exploring Knowledge Management tools and techniques within the changing landscape of the pharmaceutical industry.
First published in 1984, this book examines corporate crime in the pharmaceutical industry. Based on extensive research, including interviews with 131 senior executives of pharmaceutical companies in the United States, the United Kingdom, Australia, Mexico and Guatemala, the book is a major study of white-collar crime. Written in the 1980s, it covers topics such as international bribery and corruption, fraud in the testing of drugs and criminal negligence in the unsafe manufacturing of drugs. The author considers the implications of his findings for a range of strategies to control corporate crime, nationally and internationally.
On its present course, the US faces a world of rising new countries that will compete with it ever more fiecely as its own power is declining. In order to slow and improve this steady leakage of power, the US must change course internationally, economically and domestically. It must also restructure to remain the world's most competitive economy. And it must address quality of life issues and fairness at home. But American politics is broken -- competing forces and interests have led to stasis. With change so tough, where now for a country where the middle classes are suffering as they have never suffered before, the pensions crisis is growing, the deficit out of sight, and radicalism waiting in the wings?
Release on 2005-12-05 | by G. Festel,A. Kreimeyer,U. Oels,Maximilian von Zedtwitz
Opportunities and Threats for Foreign Companies
Author: G. Festel,A. Kreimeyer,U. Oels,Maximilian von Zedtwitz
Pubpsher: Springer Science & Business Media
Category: Business & Economics
A detailed examination of China’s increasingly important chemical and pharmaceutical industry. Numerous case studies describe how western companies, such as BASF, Bayer, Bicoll, Ciba, Degussa, DSM and Novartis are managing their market entry in China.
The medical achievements of the post-war years rank as one of the supreme epochs of human endeavour. Advances in surgical technique, new ideas about the nature of disease and huge innovations in drug manufacture vanquished most common causes of early death, But, since the mid-1970s the rate of development has slowed, and the future of medicine is uncertain. How has this happened? James Le Fanu's hugely acclaimed survey of the 'twelve definitive moments' of modern medicine and the intellectual vacuum which followed them has been fully revised and updated for this edition. The Rise and Fall of Modern Medicine is both riveting drama and a clarion call for change.
Models for New Product and In-Market Forecasting and How to Use Them
Author: Mr Arthur G Cook
Pubpsher: Gower Publishing, Ltd.
The author explores the pharmaceutical forecasting process; the varied tools and methods for new product and in-market forecasting; how they can be used to communicate market dynamics to the various stakeholders; and the strengths and weaknesses of different forecast approaches.
For readers interested in becoming a pharmacy technician, manufacturing technician, pharmaceutical sales representative, pharmacy billing specialist, pharmacy records manager, or pharmacy clerk, among other jobs, this guide encourages them to start doing their homework now by taking any high school, honors, college prep, or community college science and math classes available. Invaluable information regarding job training, certification, and associate's degrees is provided. The relative merits and advantages of online, community college, traditional university, and 2- and 4-year programs are analyzed and discussed. Networking is also emphasized. This valuable volume will help direct readers to a great pharmaceutical industry career.